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Renal plasma flow, filtration fraction and microalbuminuria in hypertensive patients: Effects of chronic smoking.
- Source :
-
Nephrology . Oct2005, Vol. 10 Issue 5, p483-486. 4p. - Publication Year :
- 2005
-
Abstract
- Introduction: Albumin excretion rate is usually increased in people who smoke, but the physiological basis of this phenomenon is not fully understood. Methods: The effect of chronic smoking on renal haemodynamics was studied in a cohort of 66 men. Twenty-seven were smokers and 36 were hypertensive. In all subjects, the albumin excretion rate was evaluated; in hypertensive patients, a renoscintigraphic evaluation of renal plasma flow and glomerular filtration were carried out and the filtration fraction was calculated. Results: The hypertensive smoking population presented an increased urinary albumin excretion rate in comparison with hypertensive non-smoking patients. No significant differences were found for the mean values of renal plasma flow, the glomerular filtration rate and the filtration fraction between hypertensive smokers and hypertensive non-smoking patients. Conclusions: In hypertensive patients, smoking does not modify typical renal haemodynamic changes of arterial hypertension; however, it significantly increases the albumin excretion rate. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13205358
- Volume :
- 10
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Nephrology
- Publication Type :
- Academic Journal
- Accession number :
- 18515165
- Full Text :
- https://doi.org/10.1111/j.1440-1797.2005.00458.x