Caspases and caspase inhibitors.

Authors :: Villa, Pascal
Kaufmann, Scott H.
Earnshaw, William C.
Source :: Trends in Biochemical Sciences. Oct97, Vol. 22 Issue 10, p388. 6p. 1 Black and White Photograph, 3 Diagrams, 1 Chart.
Publication Year :: 1997
Abstract: Dicusses the two classes of caspases, the reasons why humans may have so many caspase genes, the growing list of caspase substrates, and viral and pharmacological caspase inhibitors. Definition of apoptosis; Identification and evaluation of caspase substrates; Reason why identification of caspases is becoming a growth industry; Caspase activation.