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Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus
- Source :
-
Bioorganic & Medicinal Chemistry Letters . Dec2005, Vol. 15 Issue 23, p5311-5314. 4p. - Publication Year :
- 2005
-
Abstract
- Abstract: Efforts directed to identifying potent HIV protease inhibitors (PI) have yielded a class of compounds that are not only very active against wild-type (NL4-3) HIV virus but also very potent against a panel of PI-resistant viral isolates. Chemistry and biology are described. [Copyright &y& Elsevier]
- Subjects :
- *PROTEASE inhibitors
*PHYSICAL sciences
*LIFE sciences
*STRUGGLE
Subjects
Details
- Language :
- English
- ISSN :
- 0960894X
- Volume :
- 15
- Issue :
- 23
- Database :
- Academic Search Index
- Journal :
- Bioorganic & Medicinal Chemistry Letters
- Publication Type :
- Academic Journal
- Accession number :
- 18950855
- Full Text :
- https://doi.org/10.1016/j.bmcl.2005.08.072