Back to Search
Start Over
Serial MR imaging and 1H-MR spectroscopy of unidentified bright objects in a case of neurofibromatosis type 1
- Source :
-
Brain & Development . Dec2005, Vol. 27 Issue 8, p595-597. 3p. - Publication Year :
- 2005
-
Abstract
- Abstract: Serial study using MR imaging and 1H-MR spectroscopy (1H-MRS) of unidentified bright objects (UBO) in a 9-year-old boy with neurofibromatosis type 1 (NF1) is described. UBO was indicated in the left globus pallidum at 3 years old, then appeared in the right globus pallidum at 5 years old along with left hemiconvulsion. These UBO gradually disappeared over several years. On 1H-MRS, the ratios of N-acetylaspartate (NAA)/creatine and that of choline/creatine were each mildly reduced in the UBO. These ratios improved in parallel with disappearance of the UBO. In addition, elevation of the lactate/lipid peak was shown in UBO during the early stage, however, it disappeared in the latter. The longitudinal follow-up using MR image and 1H-MRS was useful for metabolic evaluation of UBO in patients with NF1. [Copyright &y& Elsevier]
- Subjects :
- *SPECTRUM analysis
*VITAMIN B complex
*GLYCINE
*CREATINE
Subjects
Details
- Language :
- English
- ISSN :
- 03877604
- Volume :
- 27
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Brain & Development
- Publication Type :
- Academic Journal
- Accession number :
- 19059869
- Full Text :
- https://doi.org/10.1016/j.braindev.2005.02.008