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Effects of Salvia Essential Oils on the Chorioallantoic Membrane (CAM) Assay.
- Source :
-
Pharmaceutical Biology . Nov2005, Vol. 43 Issue 8, p666-671. 6p. 3 Charts. - Publication Year :
- 2005
-
Abstract
- The aerial parts of Salvia hedgeana Dönmez, Salvia huberi Hedge, Salvia pisidica Boiss. & Heldr. ex Bentham. were subjected to hydrodistillation. The obtained essential oils were analyzed both by gas chromatography (GC) and gas chromatography-mass spectrometry (GC-MS). The analyses showed that S. hedgeana essential oil consisted of β-pinene (30.0%) as a major component, in addition to 65 identified components, representing 89.9% of the total essential oil. The major component of S. huberi was identified as 1,8-cineole (20.4%), and 76 further components were characterized representing 87.6%. S. pisidica essential oil revealed the occurrence of camphor (21.7%) as the main constituent among another 59 identified components of 76.8% of the total. Furthermore, the biological properties of the analyzed essential oils were tested using the in vivo method on the chorioallantoic membrane (CAM) in order to examine the anti-inflammatory and anti-angiogenic activity as well as possible irritant or toxic side effects. All essential oils tested at a concentration of 100 µg/pellet showed no pronounced anti-inflammatory, angiogenic, or membrane-toxic properties. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 13880209
- Volume :
- 43
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Pharmaceutical Biology
- Publication Type :
- Academic Journal
- Accession number :
- 19328588
- Full Text :
- https://doi.org/10.1080/13880200500383397