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Kehokorins A–C, novel cytotoxic dibenzofurans isolated from the myxomycete Trichia favoginea var. persimilis

Authors :
Kaniwa, Kouken
Ohtsuki, Takashi
Yamamoto, Yukinori
Ishibashi, Masami
Source :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry. Mar2006, Vol. 47 Issue 10, p1505-1508. 4p.
Publication Year :
2006

Abstract

Abstract: Kehokorins A ( 1 )–C ( 3 ), three novel dibenzofurans, have been isolated from field-collected fruit bodies of the myxomycete, Trichia favoginea var. persimilis, and their structures were elucidated by spectral data. Kehokorin A ( 1 ) was a α-l-rhamnopyranoside of kehokorin B ( 2 ), while kehokorin C ( 3 ) was a 1-demethoxy analog of 2 . Kehokorin A ( 1 ) was cytotoxic against HeLa cells with an IC50 value of 1.5μg/mL. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
00404039
Volume :
47
Issue :
10
Database :
Academic Search Index
Journal :
Tetrahedron Letters: International Organ for the Rapid Publication of Preliminary Communications in Organic Chemistry
Publication Type :
Academic Journal
Accession number :
19589178
Full Text :
https://doi.org/10.1016/j.tetlet.2006.01.012