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Protein Recognition via Surface Molecularly Imprinted Polymer Nanowires.
- Source :
-
Analytical Chemistry . 1/1/2006, Vol. 78 Issue 1, p317-320. 4p. - Publication Year :
- 2006
-
Abstract
- In this paper, we present a technique for the preparation of polymer nanowires with the protein molecule imprinted and binding sites at surface. These surface imprinting nanowires exhibit highly selective recognition for a variety of template proteins, including albumin, hemoglobin, and cytochrome c. This recognition may be through a multi-step adsorption, with the specificity conferred by hydrogen bonding and shape selectivity. Due to the protein imprinted sites are located at, or close to, the surface; these imprinted nanowires have a good site accessibility toward the target protein molecules. Furthermore, the large surface area of the nanowires results in large protein molecule binding capacity of the imprinted nanowires. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00032700
- Volume :
- 78
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Analytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 19903759
- Full Text :
- https://doi.org/10.1021/ac050802i