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Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated...

Authors :
Warner, Timothy D.
Giuliano, Francesco
Source :
Proceedings of the National Academy of Sciences of the United States of America. 06/22/99, Vol. 96 Issue 13, p7563. 6p. 1 Chart, 4 Graphs.
Publication Year :
1999

Abstract

Presents information on a study that reported data from human whole blood assay and a modified human whole blood assay for the association of nonsteroid anti-inflammatory drugs (NSAID) with inhibition of cyclo-oxygenase (COX)-2 with -1. Methodology of the study; Production of prostanoid; Inhibitor potencies of COX-2 and -2.

Details

Language :
English
ISSN :
00278424
Volume :
96
Issue :
13
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
2019496
Full Text :
https://doi.org/10.1073/pnas.96.13.7563