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Specificity of native-like interhelical hydrophobic contacts in the apomyoglobin intermediate.

Authors :
Kay, Michael S.
Ramos, Carlos H.I.
Source :
Proceedings of the National Academy of Sciences of the United States of America. 03/02/99, Vol. 96 Issue 5, p2007. 6p. 2 Charts, 8 Graphs.
Publication Year :
1999

Abstract

Investigates the effects of mutations at helix pairing sites on the stability of the apomyoglobin intermediate I. Truncate hydrophobic side chains; Specificity of hydrophobic burial to native helix packing sites; Role of hydrophobic burial in the formation of the cooperatively folded intermediate.

Details

Language :
English
ISSN :
00278424
Volume :
96
Issue :
5
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
2023005
Full Text :
https://doi.org/10.1073/pnas.96.5.2007