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Terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase.
- Source :
-
Proceedings of the National Academy of Sciences of the United States of America . 03/02/99, Vol. 96 Issue 5, p2227. 6p. 10 Diagrams, 2 Charts, 10 Graphs. - Publication Year :
- 1999
-
Abstract
- Identifies and characterizes terreic acid, a quinone epoxide inhibitor of Bruton's tyrosine kinase (Btk). Use of in vitro assay to measure the activity that blocks the interaction between protein kinase C and terreic acid; Inhibition of enzymatic activity of Btk in mast cells and cell-free assays.
- Subjects :
- *EPOXY compounds
*QUINONE
*PROTEIN-tyrosine kinases
Subjects
Details
- Language :
- English
- ISSN :
- 00278424
- Volume :
- 96
- Issue :
- 5
- Database :
- Academic Search Index
- Journal :
- Proceedings of the National Academy of Sciences of the United States of America
- Publication Type :
- Academic Journal
- Accession number :
- 2023043
- Full Text :
- https://doi.org/10.1073/pnas.96.5.2227