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INFERRING PHYLOGENETIC RELATIONSHIPS AVOIDING FORBIDDEN ROOTED TRIPLETS.

Authors :
YING-JUN HE
HUYNH, TRINH N. D.
JANSSON, JESPER
WING-KIN SUNG
Source :
Journal of Bioinformatics & Computational Biology. Feb2006, Vol. 4 Issue 1, p59-74. 16p. 2 Color Photographs.
Publication Year :
2006

Abstract

To construct a phylogenetic tree or phylogenetic network for describing the evolutionary history of a set of species is a well-studied problem in computational biology. One previously proposed method to infer a phylogenetic tree/network for a large set of species is by merging a collection of known smaller phylogenetic trees on overlapping sets of species so that no (or as little as possible) branching information is lost. However, little work has been done so far on inferring a phylogenetic tree/network from a specified set of trees when in addition, certain evolutionary relationships among the species are known to be highly unlikely. In this paper, we consider the problem of constructing a phylogenetic tree/network which is consistent with all of the rooted triplets in a given set $\mathcal{C}$ and none of the rooted triplets in another given set $\mathcal{F}$. Although NP-hard in the general case, we provide some efficient exact and approximation algorithms for a number of biologically meaningful variants of the problem. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
02197200
Volume :
4
Issue :
1
Database :
Academic Search Index
Journal :
Journal of Bioinformatics & Computational Biology
Publication Type :
Academic Journal
Accession number :
20269890
Full Text :
https://doi.org/10.1142/S0219720006001709