Two pseudopolymorphic hydrates of brucine: brucine–water (1/4) and brucine–water (1/5.25) at 130 K.

The structures of two pseudopolymorphic hydrates of brucine, C23H26N2O4·4H2O, (I), and C23H26N2O4·5.25H2O, (II), have been determined at 130 K. In both (I) and (II) (which has two independent brucine mol­ecules together with 10.5 water mol­ecules of solvation in the asymmetric unit), the brucine mol­ecules form head-to-tail sheet substructures, which associate with the water mol­ecules in the inter­stitial cavities through hydrogen-bonding associations and, together with water–water associations, give three-dimensional framework structures. [ABSTRACT FROM AUTHOR]