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The rising trend of invasive zygomycosis in patients with uncontrolled diabetes mellitus.
- Source :
-
Medical Mycology . Jun2006, Vol. 44 Issue 4, p335-342. 8p. 7 Charts, 1 Graph. - Publication Year :
- 2006
-
Abstract
- Zygomycosis is an emerging infection worldwide. A study was conducted to understand its spectrum in the Indian scenario. All patients diagnosed for invasive zygomycosis at a tertiary care center in north India from 2000–2004, were retrospectively analyzed. A total of 178 cases (mean average of 35.6 cases/year) of zygomycosis were diagnosed. Rhino-orbito-cerebral type (54.5%) was the commonest presentation followed by cutaneous (14.6%), disseminated (9.0%), and gastrointestinal (8.4%) zygomycosis. Renal and pulmonary zygomycosis were seen in 6.7% patients each. Uncontrolled diabetes mellitus (in 73.6% of cases) was the significant risk factor in all types (Odds Ratio 1.5–8.0) except renal zygomycosis. Breach of skin was the risk factor in 46.2% patients with cutaneous zygomycosis. However, no risk factor could be detected in 11.8% patients. Antemortem diagnosis was possible in 83.7% cases. The commonest (61.5%) isolate was Rhizopus oryzae followed by Apophysomyces elegans in 27% patients. Combination of debridement surgery and amphotericin B therapy was significantly better in survival of the patients ( P [ABSTRACT FROM AUTHOR]
- Subjects :
- *ZYGOMYCETES
*DIABETES
*INFECTION
*WOUND care
*MYCOSES
Subjects
Details
- Language :
- English
- ISSN :
- 13693786
- Volume :
- 44
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Medical Mycology
- Publication Type :
- Academic Journal
- Accession number :
- 21143857
- Full Text :
- https://doi.org/10.1080/13693780500464930