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In vitro binding of bile acids and triglycerides by selected chitosan preparations and their physico-chemical properties
- Source :
-
LWT - Food Science & Technology . Dec2006, Vol. 39 Issue 10, p1087-1092. 6p. - Publication Year :
- 2006
-
Abstract
- Abstract: The selected 11 chitosan samples were evaluated for their fat- and bile acid-binding capacities, physico-chemical properties, and the correlations between each binding capacity and individual physico-chemical properties. The bile acid- and fat-binding capacities were estimated using in vitro assays, whereas the measured physico-chemical properties were deacetylation degree, swelling capacity, and solution viscosity. Chitosan samples might differ in their binding capacities against fat and/or individual bile acids. The bile acid-binding capacities were 0.20–0.61, 0.43–1.63, and 0.61–1.61μmol/g chitosan for cholic, deoxycholic, and chenodeoxycholic acids, respectively. Stronger binding capacity of chitosan against a selected bile acid does not warrant greater binding capacity for other bile acid. The fat-binding capacity ranged from 1077–1239g oil/g for the chitosan samples under the experimental conditions. No correlation was observed between any binding ability and individual physico-chemical properties, although the swelling capacity of chitosan was correlated to the solution viscosity (, ) and deacetylation degree (, ), indicating that none of the measured physico-chemical properties can be used to predict the fat- or bile acid-binding ability of chitosan. [Copyright &y& Elsevier]
- Subjects :
- *BILE acids
*BILIARY tract
*EDEMA
*FAT
Subjects
Details
- Language :
- English
- ISSN :
- 00236438
- Volume :
- 39
- Issue :
- 10
- Database :
- Academic Search Index
- Journal :
- LWT - Food Science & Technology
- Publication Type :
- Academic Journal
- Accession number :
- 21275529
- Full Text :
- https://doi.org/10.1016/j.lwt.2005.07.009