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Mapping the sensitivity of T cells with an optical trap: Polarity and minimal number of receptors...

Authors :
Wei, Xunbin
Tromberg, Bruce J.
Source :
Proceedings of the National Academy of Sciences of the United States of America. 07/20/99, Vol. 96 Issue 15, p8471. 6p. 1 Color Photograph, 1 Chart, 2 Graphs.
Publication Year :
1999

Abstract

Addresses the spatial and temporal contact requirements for T cell activation and minimum number of receptors that must be engaged to transmit a calcium signal. Cell culture; Antibody coating on beads; Optical trapping; Contact-area estimation; Discussion on T cell functional polarity identified with an optical trap.

Subjects

Subjects :
*T cells
*CELL culture

Details

Language :
English
ISSN :
00278424
Volume :
96
Issue :
15
Database :
Academic Search Index
Journal :
Proceedings of the National Academy of Sciences of the United States of America
Publication Type :
Academic Journal
Accession number :
2129241
Full Text :
https://doi.org/10.1073/pnas.96.15.8471