Cu-catalyzed cross-dehydrogenative coupling: A versatile strategy for C–C bond formations via the oxidative activation of sp3 C–H bonds.

Authors :: Zhiping Li
Bohle, D. Scott
Chao-Jun Li
Source :: Proceedings of the National Academy of Sciences of the United States of America. 6/13/2006, Vol. 103 Issue 24, p8928-8933. 6p. 11 Diagrams, 7 Charts.
Publication Year :: 2006
Abstract: Cu-catalyzed cross-dehydrogenative coupling (CDC) methodologies were developed based on the oxidative activation of sp3 C-H bonds adjacent to a nitrogen atom. Various sp, sp2, and sp3 C-H bonds of pronucleophiles were used in the Cu-catalyzed CDC reactions. Based on these results, the mechanisms of the CDC reactions also are discussed. [ABSTRACT FROM AUTHOR]

Subjects :: *CHEMICAL bonds
*CATALYSIS
*MANNICH reaction
*FRIEDEL-Crafts reaction
*CHEMICAL reactions
*CHEMICAL structure

Language :: English
ISSN :: 00278424
Volume :: 103
Issue :: 24
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 21402954
Full Text :: https://doi.org/10.1073/pnas.0601687103

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