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RNA Folding During Transcription.
- Source :
-
Annual Review of Biophysics & Biomolecular Structure . 2006, Vol. 35 Issue 1, p161-175. 15p. - Publication Year :
- 2006
-
Abstract
- The evolution of RNA sequence needs to satisfy three requirements: folding, structure, and function. Studies on folding during transcription are related directly to folding in the cell. Understanding RNA folding during transcription requires the elucidation of structure formation and structural changes of the RNA, and the consideration of intrinsic properties of the RNA polymerase and other proteins that interact with the RNA. This review summarizes the research progress in this area and outlines the enormous challenges facing this field. Significant advancement requires the development of new experimental methods and theoretical considerations in all aspects of transcription and RNA folding. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NUCLEOTIDE sequence
*RNA polymerases
*CATALYTIC RNA
*CELLS
*NUCLEIC acid analysis
Subjects
Details
- Language :
- English
- ISSN :
- 10568700
- Volume :
- 35
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- Annual Review of Biophysics & Biomolecular Structure
- Publication Type :
- Academic Journal
- Accession number :
- 21417116
- Full Text :
- https://doi.org/10.1146/annurev.biophys.35.040405.102053