Back to Search Start Over

Discovery of a novel, potent, and specific family of factor Xa inhibitors via combinatorial...

Authors :
Ostrem, James A.
Al-Obeidi, Fahad
Safar, Pavel
Safarova, Alena
Stringer, Steven K.
Patek, Marcel
Cross, M. Todd
Spoonamore, James
LoCascio, Jeff C.
Kasireddy, Padmaja
Thorpe, David S.
Sepetov, Nikolai
Lebl, Michal
Wildgoose, Peter
Strop, Peter
Source :
Biochemistry. 01/27/98, Vol. 37 Issue 4, p1053. 7p. 3 Charts, 8 Graphs.
Publication Year :
1998

Abstract

Identifies a series of low molecular weight peptide inhibitors for factor Xa, by screening a peptide library composed of L-amino acids. Methodology used in the study; Results of the study; Discussion of the results of the study.

Subjects

Subjects :
*PEPTIDES
*AMINO acids

Details

Language :
English
ISSN :
00062960
Volume :
37
Issue :
4
Database :
Academic Search Index
Journal :
Biochemistry
Publication Type :
Academic Journal
Accession number :
215951
Full Text :
https://doi.org/10.1021/bi971147e