Developments in pharmacological therapy for the overactive bladder.

The article provides a summary of developments in pharmacological therapy for the overactive bladder (OAB), particularly with regards to available antimuscarinic drugs and the newer non-anticholinergic drugs. Antimuscarinic drugs include tolterodine, trospium, darifenacin and solifenacin. Other types of drugs are those acting on membrane channels, those with mixed actions, adrenoceptors, antidepressants, prostaglandin synthesis inhibitors and vasopressin analogues.