Tumor Necrosis Factor-α.

The article provides information on tumor necrosis factor (TNF)-α. TNF-α is a pleiotropic inflammatory cytokine that mediates roles in homeostasis, cell growth and tissue damage. The stimuli that trigger the production of TNF-α include bacterial products, oxidative stress and other cytokines. Moreover, the relevance of TNF-α with immunotoxicity and humans is discussed.