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Synthesis of ω-(Hetero)arylalkynylated α-Amino Acid by Sonogashira-Type Reactions in Aqueous Media.

Authors :
Brea, Roberto J.
López-Deber, M. Pilar
Castedo, Luis
Granja, Juan R.
Source :
Journal of Organic Chemistry. 9/29/2006, Vol. 71 Issue 20, p7870-7873. 4p. 1 Diagram, 1 Chart.
Publication Year :
2006

Abstract

Mild conditions are described that allow the palladium-catalyzed cross-coupling of Cα-alkynylated glycine with a wide variety of electron-rich and electron-poor aryl and heteroaryl halides in aqueous media. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
00223263
Volume :
71
Issue :
20
Database :
Academic Search Index
Journal :
Journal of Organic Chemistry
Publication Type :
Academic Journal
Accession number :
22837610
Full Text :
https://doi.org/10.1021/jo061300n