Retrobulbar haemodynamics in non-arteritic anterior ischaemic optic neuropathy.

Aim: To compare retrobulbar haemodynamics in patients with acute non-arteritic anterior ischaemic optic neuropathy (NAION) and age-matched controls by colour Doppler imaging (CDI). Methods: 25 patients with acute NAION and 35 age-matched controls participated in this study. By means of CDI, the blood flow velocities of the ophthalmic artery, central retinal artery (CRA), and nasal and temporal short posterior ciliary arteries (PCAs) were measured. Peak-systolic velocity (PSY) and end-diastolic velocity (EDY) and Pourcelot's resistive index were determined. Results: In the ophthalmic artery, no marked differences between patients with NAION and controls were detected. PSV and EDV of the CRA (p<0.001, p = 0.002) and PSV of the nasal PCA (p<0.05) were significantly decreased in patients with NAION compared with healthy controls. No marked differences between patients and controls were detectable for temporal PCAs. Conclusion: Blood flow velocities of the nasal PCA and the CRA are considerably reduced in patients with acute NAION compared with controls. Patients with NAION in part showed markedly different retrobulbar haemodynamics. [ABSTRACT FROM AUTHOR]