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Quantification of seven arsenic compounds in seafood products by liquid chromatography/electrospray ionization-single quadrupole mass spectrometry (LC/ESI-MS).
- Source :
-
Food Additives & Contaminants . Dec2006, Vol. 23 Issue 12, p1299-1307. 9p. 3 Charts, 3 Graphs. - Publication Year :
- 2006
-
Abstract
- A liquid chromatography/electrospray ionization-single quadrupole mass spectrometry (LC/ESI-MS) method was developed to quantify seven arsenic compounds: arsenate (As(V)), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA), arsenobetaine (AB), trimethylarsine oxide (TMAO), arsenocholine (AC) and tetramethylarsonium ion (TEMA), widely found in seafood. The arsenicals separated by anion- or cation-exchange LC were all readily identified under the optimized ESI-MS conditions. Linear calibration curves constructed by plotting the peak area counts of molecular ions against the arsenic concentrations were obtained for all seven arsenic compounds. The limits of quantification (S/N = 10) were 800, 600, 50, 10, 5, 5 and 5 ng ml-1 for As(V), MMA, DMA, AB, TMAO, AC and TEMA, respectively. The LC/ESI-MS method was found to be useful to quantify arsenic compounds in seafood by model experiments using the mid-gut gland and muscle of a shellfish (Buccinid whelks). Spiking experiments verified the accuracy of the method. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 0265203X
- Volume :
- 23
- Issue :
- 12
- Database :
- Academic Search Index
- Journal :
- Food Additives & Contaminants
- Publication Type :
- Academic Journal
- Accession number :
- 23173487
- Full Text :
- https://doi.org/10.1080/02652030600815355