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Decreased peritoneal concentrations of interleukin-15 in women with advanced stage endometriosis
- Source :
-
European Journal of Obstetrics & Gynecology & Reproductive Biology . Dec2006, Vol. 129 Issue 2, p169-173. 5p. - Publication Year :
- 2006
-
Abstract
- Abstract: Objective: To assess the concentrations of interleukin-15 (IL-15) in peritoneal fluid from women with endometriosis and fertile disease-free controls. Study design: Peritoneal fluid samples were obtained from 50 women with endometriosis and 29 fertile women having tubal ligation. Concentrations of IL-15 were measured. Results: The mean (S.D.s) concentration of IL-15 in peritoneal fluid was 11.17pg/mL (3.89) for women with endometriosis, and 12.59pg/mL (4.11) for fertile disease-free controls. The difference of peritoneal IL-15 concentrations between endometriosis and control women was not statistically significant. However, peritoneal IL-15 concentrations were significantly lower in women with moderate/severe endometriosis when compared with those in women with minimal/mild endometriosis, and in controls (P <0.05). In addition, peritoneal IL-15 concentrations did not correlate with the phase of menstrual cycle in endometriosis or control women. Conclusions: Our results suggest that the decreased peritoneal IL-15 concentrations in women with moderate/severe endometriosis imply a role of IL-15 in the pathogenesis of advanced endometriosis as compared to those with minimal/mild endometriosis and fertile disease-free controls. [Copyright &y& Elsevier]
- Subjects :
- *ENDOMETRIOSIS
*FEMALE reproductive organ diseases
*ENDOMETRIUM
*MENSTRUAL cycle
Subjects
Details
- Language :
- English
- ISSN :
- 03012115
- Volume :
- 129
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- European Journal of Obstetrics & Gynecology & Reproductive Biology
- Publication Type :
- Academic Journal
- Accession number :
- 23282345
- Full Text :
- https://doi.org/10.1016/j.ejogrb.2006.01.005