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THE ROLE OF GLUTAMATE TRANSPORTERS IN GLUTAMATE HOMEOSTASIS IN THE BRAIN.

Authors :
Takahashi, Michiko
Billups, Brian
Rossi, David
Sarantis, Monique
Hamann, Martine
Attwell, David
Source :
Journal of Experimental Biology. Jan1997, Vol. 200 Issue 2, p401-409. 9p. 5 Graphs.
Publication Year :
1997

Abstract

The article studies the role performed by glutamate transporters in the homeostasis of glutamate in the brain. Glutamate transporters have a crucial function in controlling the extracellular concentration of glutamate in the brain. They remove glutamate from extracellular space and help terminate glutamatergic synaptic transmission. This prevents the extracellular concentration of glutamate from rising to neurotoxic levels.

Details

Language :
English
ISSN :
00220949
Volume :
200
Issue :
2
Database :
Academic Search Index
Journal :
Journal of Experimental Biology
Publication Type :
Academic Journal
Accession number :
23636447
Full Text :
https://doi.org/10.1242/jeb.200.2.401