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Analogues of 2-crotonyloxymethyl-(4R,5R,6R)-4,5,6-trihydroxycyclohex-2-enone (COTC) with anti-tumor properties

Authors :
Arthurs, Claire L.
Wind, Natasha S.
Whitehead, Roger C.
Stratford, Ian J.
Source :
Bioorganic & Medicinal Chemistry Letters. Jan2007, Vol. 17 Issue 2, p553-557. 5p.
Publication Year :
2007

Abstract

Abstract: The syntheses of three novel analogues of the naturally occurring cytotoxic agent COTC are described and the results of bioassays of the target compounds against two lung cancer cell lines are presented. [Copyright &y& Elsevier]

Details

Language :
English
ISSN :
0960894X
Volume :
17
Issue :
2
Database :
Academic Search Index
Journal :
Bioorganic & Medicinal Chemistry Letters
Publication Type :
Academic Journal
Accession number :
23671084
Full Text :
https://doi.org/10.1016/j.bmcl.2006.09.072