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Reduced efficacy of insecticide-treated nets and indoor residual spraying for malaria control in pyrethroid resistance area, Benin.
- Source :
-
Emerging Infectious Diseases . Feb2007, Vol. 13 Issue 2, p199-206. 8p. - Publication Year :
- 2007
-
Abstract
- The pyrethroid knockdown resistance gene (kdr) has become widespread in Anopheles gambiae in West Africa. A trial to test the continuing efficacy of insecticide-treated nets (ITN) and indoor residual spraying (IRS) was undertaken in experimental huts at 2 sites in Benin, the first where kdr is present at high frequency (Ladji), the second-where An. gambiae is susceptible (Malanville). Holes were made in the nets to mimic worn nets. At Malanville, 96% of susceptible An. gambiae were inhibited from blood-feeding, whereas at Ladji feeding was uninhibited by ITNs. The mortality rate of An. gambiae in ITN huts was 98% in Malanville but only 30% at Ladji. The efficacy of IRS was equally compromised. Mosquitoes at Ladji had higher oxidase and esterase activity than in a laboratory-susceptible strain, but this fact did not seem to contribute to resistance. Pyrethroid resistance in An. gambiae appears to threaten the future of ITN and IRS in Benin. [ABSTRACT FROM AUTHOR]
- Subjects :
- *NETS
*INSECTICIDES
*SPRAYING
*MALARIA
*PYRETHROIDS
*ANOPHELES gambiae
*MOSQUITOES
Subjects
Details
- Language :
- English
- ISSN :
- 10806040
- Volume :
- 13
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Emerging Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 23887180
- Full Text :
- https://doi.org/10.3201/eid1302.060631