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The distribution of hereditary erythrocytic disorders associated with malaria, in a lowland area of Nepal: a micro-epidemiological study.
- Source :
-
Annals of Tropical Medicine & Parasitology . Mar2007, Vol. 101 Issue 2, p113-122. 10p. 5 Charts, 2 Graphs. - Publication Year :
- 2007
-
Abstract
- Among four ethnic groups in a lowland area of Nepal, the prevalences of abnormal haemoglobin, thalassaemia, glucose-6-phosphate-dehydrogenase (G6PD) deficiency, hereditary South–east Asian ovalocytosis (SAO) and Duffy blood-group antigen Fy/Fy were determined and related to each group's habitat. The group that has lived for many decades in a malaria-endemic lowland area, the Danuwar, was found to have a high prevalence of α+-thalassaemia (79.4%) and low prevalences of haemoglobin E and G6PD deficiency. Much lower prevalences of α+-thalassaemia were observed in the Newar (20.5%), Parbate (16.5%) and Tamang (8.8%), who, until the 1950s, all spent their hot-season nights in malaria-free areas at higher altitudes. No subjects with any other identified abnormal haemoglobin, β-thalassaemia, SAO or Fy/Fy were detected. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00034983
- Volume :
- 101
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Annals of Tropical Medicine & Parasitology
- Publication Type :
- Academic Journal
- Accession number :
- 23969249
- Full Text :
- https://doi.org/10.1179/136485907X154539