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Aplastic Crisis as a Complication of Congenital Dyserythropoietic Anemia Type II.
- Source :
-
Acta Haematologica . Mar2007, Vol. 117 Issue 2, p115-118. 4p. 1 Chart. - Publication Year :
- 2007
-
Abstract
- A transient aplastic crisis (TAC) is a well-known complication in all types of chronic hemolytic anemia but only 2 cases of such an event were described in congenital dyserythropoietic anemias (CDAs). Here, we report a third case, and by retrospective chart review of 78 cases we found evidence of TAC in 8 further patients with CDA II, with serological evidence of previous human parvovirus B19 (B19V) infection in all but one. Although B19V infection results in TAC in only a minority of patients with CDA, physicians responsible for these patients should be aware of such a potentially life-threatening complication. Testing for B19V-specific IgG is recommended in patients with CDA to estimate the risk of a possible future aplastic crisis. Copyright © 2007 S. Karger AG, Basel [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00015792
- Volume :
- 117
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Acta Haematologica
- Publication Type :
- Academic Journal
- Accession number :
- 24006271
- Full Text :
- https://doi.org/10.1159/000097360