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Worldwide Emergence of Extensively Drug-resistant Tuberculosis.
- Source :
-
Emerging Infectious Diseases . Mar2007, Vol. 13 Issue 3, p380-387. 8p. - Publication Year :
- 2007
-
Abstract
- Mycobacterium tuberculosis strains that are resistant to an increasing number of second-line drugs used to treat multidrug-resistant tuberculosis (MDR TB) are becoming a threat to public health worldwide. We surveyed the Network of Supranational Reference Laboratories for M. tuberculosis isolates that were resistant to second-line anti-TB drugs during 2000-2004. We defined extensively drug-resistant TB (XDR TB) as MDR TB with further resistance to >3 of the 6 classes of second-line drugs. Of 23 eligible laboratories, 14 (61%) contributed data on 17,690 isolates, which reflected drug susceptibility results from 48 countries. Of 3,520 (19.9%) MDR TB isolates, 347 (9.9%) met criteria for XDR TB. Further investigation of population-based trends and expanded efforts to prevent drug resistance and effectively treat patients with MDR TB are crucial for protection of public health and control of TB. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 10806040
- Volume :
- 13
- Issue :
- 3
- Database :
- Academic Search Index
- Journal :
- Emerging Infectious Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 24274649
- Full Text :
- https://doi.org/10.3201/eid1303.061400