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Antipsychotic drug use in 503 Chinese inpatients with schizophrenia.
- Source :
-
International Journal of Psychiatry in Clinical Practice . Mar2007, Vol. 11 Issue 1, p29-35. 7p. 3 Charts. - Publication Year :
- 2007
-
Abstract
- Objective. To determine current patterns of antipsychotic medication use and metabolic complications among hospitalized Chinese patients with schizophrenia. Method. A total of 503 inpatients who met ICD-10 diagnostic criteria for schizophrenia were enrolled. Demographic features and records of current treatment (medication, dose, duration of treatment) were collected through cross-sectional chart review along with biophysical parameters (body mass index and laboratory findings). Results. (1) Most patients (457/503, 90.9%) were found to receive antipsychotic monotherapy; (2) clozapine was the most common medication used (152/507, 30.2%); (3) the subset of patients treated within the course of a first episode psychosis, or with less than 5 years of illness, were more likely to be treated with second-generation antipsychotics (SGAs) than with conventional antipsychotic medications or clozapine; (4) patients treated with clozapine or conventional antipsychotics were more likely to manifest metabolism-related physical conditions than those receiving SGAs. Conclusion. Conventional antipsychotics and clozapine constitute the current mainstream of schizophrenia treatment in China where a lower percentage of patients receive SGAs other than clozapine than in developed countries. The high incidence of treatment-related metabolic complications in this population suggests that these issues are under-appreciated based on current patterns of medication use. [ABSTRACT FROM AUTHOR]
- Subjects :
- *CLOZAPINE
*SCHIZOPHRENIA treatment
*ANTIDEPRESSANTS
*PEOPLE with schizophrenia
Subjects
Details
- Language :
- English
- ISSN :
- 13651501
- Volume :
- 11
- Issue :
- 1
- Database :
- Academic Search Index
- Journal :
- International Journal of Psychiatry in Clinical Practice
- Publication Type :
- Academic Journal
- Accession number :
- 24280566
- Full Text :
- https://doi.org/10.1080/13651500600874360