Reaction of Hydrazonoyl Halides 511: A Facile Synthesis of 5-Arylthiazoles and Triazolino[4,3-a]pyrimidines as Antimicrobial Agents.

[5-Substituted 2-(3-phenyl-5-substituted 2-pyrazolinyl)(1,3-thiazol-4-yl)]phenyldiazenes, triazolo[3,4-a]pyrimidines, and 2,3-dihydro-1,3,4-thiadiazoles were synthesized with good yields from reactions of hydrazonoyl halides with 5-substituted-3-phenyl-4,5-dihydropyrazole-1-carboximidothionic acid, pyrimidine-2-thione, methyl carbodithioate, respectively. All structures of the newly synthesized compounds were elucidated by elemental analysis, spectral data, and alternative synthesis methods. Newly developed compounds are capable of inhibiting the growth of bacteria (gram positive and gram negative) greatly. [ABSTRACT FROM AUTHOR]