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1-[1-(2-Hydroxyethyl)-6-methyl-2-phenyl-4-thioxo-1,4-dihydropyrimidin-5-yl]-1-ethanone.

Authors :
Sabino, José R.
Lariucci, Carlito
Bastos, Rodrigo M.
Cunha, Silvio
Source :
Acta Crystallographica: Section E. Jun2007, Vol. 63 Issue 6, po2850-o2850. 1p. 4 Diagrams, 1 Chart.
Publication Year :
2007

Abstract

The title compound, C15H16N2O2S, is of interest with respect to antibacterial and anticancer activity and shows some trypanocidal activity. The crystal structure displays O—H...N hydrogen bonding, forming a chain along [001]. A weak non-classical hydrogen bond of type C—H...S connects molecules across an inversion centre. The packing is also mediated by an intermolecular C=O...π ring interaction connecting centrosymmetrically related molecules. Steric effects are responsible for the molecular conformation. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
16005368
Volume :
63
Issue :
6
Database :
Academic Search Index
Journal :
Acta Crystallographica: Section E
Publication Type :
Academic Journal
Accession number :
25439532
Full Text :
https://doi.org/10.1107/S1600536807019940