Asymmetric Synthesis of syn--Substituted -Amino Ketones by Using Sulfinimines and Prochiral Weinreb Amide Enolates.

syn--Substituted -amino Weinreb amides are new chiral building blocks for asymmetric synthesis of syn--substituted -amino acids, aldehydes, and ketones and are prepared by addition of prochiral lithium enolates of Weinreb amides to sulfinimines (N-sulfinyl imines). [ABSTRACT FROM AUTHOR]