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Predicting memory: a prospective readout for malaria vaccines?
- Source :
-
Trends in Parasitology . Aug2007, Vol. 23 Issue 8, p341-343. 3p. - Publication Year :
- 2007
-
Abstract
- Malaria vaccines aim to induce long lasting protective immunity. Bejon and colleagues propose that levels of rapidly induced (effector memory) interleukin-2 and interferon gamma producing T-cells after vaccination with leading pre-erythrocytic stage vaccines predict the induction of resting memory responses (central memory). Herein we discuss Bejon''s findings in the context of current thinking on the generation and maintenance of T cell memory, with particular emphasis on the role of cytokines. [Copyright &y& Elsevier]
- Subjects :
- *MALARIA
*VACCINES
*IMMUNITY
*INTERLEUKIN-2
*INTERFERONS
*VACCINATION
Subjects
Details
- Language :
- English
- ISSN :
- 14714922
- Volume :
- 23
- Issue :
- 8
- Database :
- Academic Search Index
- Journal :
- Trends in Parasitology
- Publication Type :
- Academic Journal
- Accession number :
- 25827231
- Full Text :
- https://doi.org/10.1016/j.pt.2007.06.006