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Surface-Imprinted Core—Shell Nanoparticles for Sorbent Assays.
- Source :
-
Analytical Chemistry . 7/15/2007, Vol. 79 Issue 14, p5457-5461. 5p. 2 Graphs. - Publication Year :
- 2007
-
Abstract
- In this paper, we present a general protocol for the making of surface-imprinted core—shell nanoparticles via surface reversible addition-fragmentation chain—transfer (RAFT) polymerization using RAFT agent functionalized model silica nanoparticles as the chain-transfer agent. In this protocol, trichloro(4-chloromethylphenyl)silane was immobilized on the surface of SiO2 nanoparticles, forming chloromethylphenyl functionalized silica (silica-Cl). RAFT agent functionalized silica was subsequently produced by substitute reaction of silica-Cl with PhC(S)SMgBr. The grafting copolyinerization of 4-vinylpyridine and ethylene glycol dimethacrylate using surface RAFT polymerization and in the presence of 2,4-dichiorophenoxyacetic acid as the template led to the formation of surface-imprinted core—shell nanoparticles The resulting surface-imprinted core—shell nanoparticles bind the original template 2,4-D with an appreciable selectivity over structurally related compounds. The potential use of the surface-imprinted core—shell nanoparticles as the recognition element in the competitive fluorescent binding assay for 2,4-D was also demonstrated. [ABSTRACT FROM AUTHOR]
Details
- Language :
- English
- ISSN :
- 00032700
- Volume :
- 79
- Issue :
- 14
- Database :
- Academic Search Index
- Journal :
- Analytical Chemistry
- Publication Type :
- Academic Journal
- Accession number :
- 25917552
- Full Text :
- https://doi.org/10.1021/ac070282m