SmartPET: Applying HPGe and pulse shape analysis to small-animal PET

Authors :: Cooper, R.J.
Boston, A.J.
Boston, H.C.
Cresswell, J.R.
Grint, A.N.
Mather, A.R.
Nolan, P.J.
Scraggs, D.P.
Turk, G.
Hall, C.J.
Lazarus, I.
Berry, A.
Beveridge, T.
Gillam, J.
Lewis, R.A.
Source :: Nuclear Instruments & Methods in Physics Research Section A. Aug2007, Vol. 579 Issue 1, p313-317. 5p.
Publication Year :: 2007
Abstract: Abstract: The SmartPET project is the development of a prototype small-animal imaging system based on the use of Hyperpure Germanium (HPGe) detectors. The use of digital electronics and application of Pulse Shape Analysis (PSA) techniques provide fine spatial resolution, while the excellent intrinsic energy resolution of HPGe detectors makes the system ideal for multi-nuclide imaging. As a result, the SmartPET system has the potential to function as a dual modality imager, operating as a dual-head Positron Emission Tomography (PET) camera or in a Compton Camera configuration for Single Photon Emission Computed Tomography (SPECT) imaging. In this paper, we discuss how the use of simple PSA techniques greatly improves the position sensitivity of the detector yielding improved spatial resolution in reconstructed images. The PSA methods presented have been validated by comparison to data from high-precision scanning of the detectors. Results from this analysis are presented along with initial images from the SmartPET system, which demonstrates the impact of these techniques on PET images. [Copyright &y& Elsevier]