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A novel analgesic pyrazine derivative from the leaves of Croton tiglium L.

Authors :
Wu, Xin-An
Zhao, Yi-Min
Yu, Neng-Jiang
Source :
Journal of Asian Natural Products Research. Jul2007, Vol. 9 Issue 5, p451-441. 5p. 1 Diagram, 1 Chart.
Publication Year :
2007

Abstract

A novel analgesic pyrazine derivative, named crotonine, was isolated from the leaves of Croton tiglium L. The structure was elucidated as 2-(furan-2-yl)-5-(2,3,4-trihydroxy-butyl)-1,4-diazine by spectroscopic analysis. Crotonine inhibited remarkably the acetic acid-induced writhing in mice. [ABSTRACT FROM AUTHOR]

Details

Language :
English
ISSN :
10286020
Volume :
9
Issue :
5
Database :
Academic Search Index
Journal :
Journal of Asian Natural Products Research
Publication Type :
Academic Journal
Accession number :
26205684
Full Text :
https://doi.org/10.1080/10286020500384781