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Long lasting BCG protection against leprosy
- Source :
-
Vaccine . Sep2007, Vol. 25 Issue 39/40, p6842-6844. 3p. - Publication Year :
- 2007
-
Abstract
- Abstract: Background: BCG vaccine protects against leprosy. Objectives: Estimate BCG protection against leprosy by age by age. Methods: A case control study with 226 cases of leprosy and 857 controls. BCG vaccination was ascertained via examination of BCG scars. Protection is presented for three age groups. Results: BCG protection against leprosy was 86% (95% CI: 77–92%) in the age group 18–29; 54% (95% CI: −37% to 85%) in the age group 30–39 and 32% (95% CI: −3% to 56%) in those aged 40 or more. Conclusions: BCG efficacy against leprosy may well last for three decades and possibly even longer. BCG vaccination must have contributed to worldwide reduction in leprosy incidence. [Copyright &y& Elsevier]
- Subjects :
- *BCG vaccines
*TUBERCULOSIS vaccines
*HANSEN'S disease
*MYCOBACTERIAL diseases
Subjects
Details
- Language :
- English
- ISSN :
- 0264410X
- Volume :
- 25
- Issue :
- 39/40
- Database :
- Academic Search Index
- Journal :
- Vaccine
- Publication Type :
- Academic Journal
- Accession number :
- 26577080
- Full Text :
- https://doi.org/10.1016/j.vaccine.2007.07.032