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The Fusarium graminearum Genome Reveals a Link Between Localized Polymorphism and Pathogen Specialization.
- Source :
-
Science . 9/7/2007, Vol. 317 Issue 5843, p1400-1402. 3p. - Publication Year :
- 2007
-
Abstract
- We sequenced and annotated the genome of the filamentous fungus Fusarium graminearum, a major pathogen of cultivated cereals. Very few repetitive sequences were detected, and the process of repeat-induced point mutation, in which duplicated sequences are subject to extensive mutation, may partially account for the reduced repeat content and apparent low number of paralogous (ancestrally duplicated) genes. A second strain of F. graminearum contained more than 10,000 single-nucleotide polymorphisms, which were frequently located near telomeres and within other discrete chromosomal segments. Many highly polymorphic regions contained sets of genes implicated in plant-fungus interactions and were unusually divergent, with higher rates of recombination. These regions of genome innovation may result from selection due to interactions of F. graminearum with its plant hosts. [ABSTRACT FROM AUTHOR]
- Subjects :
- *FUSARIUM
*GRASSES
*GENOMES
*PATHOGENIC microorganisms
*GRAIN
*GENES
*TELOMERES
*PLANTS
Subjects
Details
- Language :
- English
- ISSN :
- 00368075
- Volume :
- 317
- Issue :
- 5843
- Database :
- Academic Search Index
- Journal :
- Science
- Publication Type :
- Academic Journal
- Accession number :
- 26652179
- Full Text :
- https://doi.org/10.1126/science.1143708