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Structural characterization of an active polysaccharide from Phellinus ribis
- Source :
-
Carbohydrate Polymers . Nov2007, Vol. 70 Issue 4, p386-392. 7p. - Publication Year :
- 2007
-
Abstract
- A water-soluble polysaccharide named as PRP was isolated from the fruiting bodies of Phellinus ribis by hot water extraction, DEAE-cellulose and Superdex 30 column chromatography. Its structural characteristics were investigated by FT-IR, NMR spectroscopy, GLC-MS, methylation analysis, periodate oxidation and Smith degradation. Based on the data obtained, PRP was found to be a β-d-glucan containing a (1→4), (1→6)-linked backbone, with a single β-d-glucose at the C-3 position of (1→6)-linked glucosyl residue every eight residues, along the main chain. The glucan has a weight-average molecular weight of about 8.59kDa by HPGPC determination using dextran samples as the standards. Preliminary activity tests in vitro revealed that PRP could stimulate the proliferation of spleen lymphocyte. [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 01448617
- Volume :
- 70
- Issue :
- 4
- Database :
- Academic Search Index
- Journal :
- Carbohydrate Polymers
- Publication Type :
- Academic Journal
- Accession number :
- 26680891
- Full Text :
- https://doi.org/10.1016/j.carbpol.2007.04.019