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Giving APCmin fumours a SPARC.

Authors :
Gregorieff, Alex
Clevers, Hans
Source :
Gut. Oct2007, Vol. 56 Issue 10, p1341-1343. 3p. 1 Chart.
Publication Year :
2007

Abstract

A new study identifies the extracellular matrix (ECM) component, SPARC (secreted protein acidic, rich in cysteine), as a critical determinant of tumour burden in the APCmin/+ model of intestinal cancer. [ABSTRACT FROM AUTHOR]

Subjects

Subjects :
*EXTRACELLULAR matrix
*CONNECTIVE tissues
*EXTRACELLULAR space
*INTERPHOTORECEPTOR matrix
*CYSTEINE proteinases
*PROTEINASES

Details

Language :
English
ISSN :
00175749
Volume :
56
Issue :
10
Database :
Academic Search Index
Journal :
Gut
Publication Type :
Academic Journal
Accession number :
27148455
Full Text :
https://doi.org/10.1136/gut.2007.122135
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