Back to Search
Start Over
Most MCF7 and SK-OV3 cells were deprived of their stem nature by Hoechst 33342
- Source :
-
Biochemical & Biophysical Research Communications . Dec2007, Vol. 364 Issue 2, p338-343. 6p. - Publication Year :
- 2007
-
Abstract
- Abstract: Using clonal and population analysis, we found that the MCF7 and SK-OV3 were composed mainly of cancer stem cells. Together with SP analysis, we found that both SP and NSP cells of MCF7 and SK-OV3 contained different proportions of cancer stem cells. In addition, we discovered that MCF7 SP cells were able to generate non-SP cells, and conversely non-SP cells generated SP cells; Moreover, we showed that Hoechst 33342 and FACS were harmful to the clonogenicity of MCF7 and SK-OV3 cells. [Copyright &y& Elsevier]
- Subjects :
- *STEM cells
*CANCER
*EMBRYONIC stem cells
*NEURAL stem cells
Subjects
Details
- Language :
- English
- ISSN :
- 0006291X
- Volume :
- 364
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- Biochemical & Biophysical Research Communications
- Publication Type :
- Academic Journal
- Accession number :
- 27227877
- Full Text :
- https://doi.org/10.1016/j.bbrc.2007.10.016