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Severe Enteropathy Among Patients With Stage II/III Colon Cancer Treated on a Randomized Trial of Bolus 5-Fluorouracil/Leucovorin Plus or Minus Oxaliplatin.
Severe Enteropathy Among Patients With Stage II/III Colon Cancer Treated on a Randomized Trial of Bolus 5-Fluorouracil/Leucovorin Plus or Minus Oxaliplatin.
- Source :
-
Cancer (0008543X) . Nov2007, Vol. 110 Issue 9, p1945-1950. 6p. 1 Black and White Photograph, 2 Charts, 1 Graph. - Publication Year :
- 2007
-
Abstract
- The article focuses on the development of severe enteropathy among patients with stage II/III colon cancer undergoing adjuvant therapy based on a clinical trial in the U.S. The patients were treated with weekly bolus 5-fluorouracil (5-FU) and leucovorin with or without oxalipatin. About 4.3% of the patients developed a syndrome of bowel wall injury (BWI) and 22 patients treated with leucovorin with oxaliplatin developed enteric sepsis (ES). There were 5 deaths due to enteropathy and 3 related to both BWI and ES.
Details
- Language :
- English
- ISSN :
- 0008543X
- Volume :
- 110
- Issue :
- 9
- Database :
- Academic Search Index
- Journal :
- Cancer (0008543X)
- Publication Type :
- Academic Journal
- Accession number :
- 27523746
- Full Text :
- https://doi.org/10.1002/cncr.23013