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AAV vectors and cardiovascular disease: Targeting TNF receptor in the heart: clue to way forward with AAV?

Authors :
Hajjar, R J
Zsebo, K
Source :
Gene Therapy. Dec2007, Vol. 14 Issue 23, p1611-1612. 2p. 1 Graph.
Publication Year :
2007

Abstract

The article focuses on studies concerning adeno-associated vectors (AAV) and cardiovascular disease. A study conducted by C.F. McTiernan may provide some clue to new pathways controlling the delicate balance between induction of deleterious T-cell responses and operational immune tolerance to the AAV2 and payload gene proteins.

Details

Language :
English
ISSN :
09697128
Volume :
14
Issue :
23
Database :
Academic Search Index
Journal :
Gene Therapy
Publication Type :
Academic Journal
Accession number :
27546197
Full Text :
https://doi.org/10.1038/sj.gt.3303047