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Immunomodulatory Role of Kupffer Cell in Liver Allografts.

Authors :
Sun, Zhaoli
Wada, Tatehiko
Hoshino, Sumito
Uchikura, Keiichiro
Klein, Andrew S.
Source :
Comparative Hepatology. 2004 Supplement 1, Vol. 3, pS32-4. 4p. 3 Graphs.
Publication Year :
2004

Abstract

A conference report on the immunomodulatory role of kupffer cell (KC)in liver allografts is presented. It zeroes in on Fas ligand expression and their role in allo-reactive T cell apoptosis in chronic accepted and acutely rejected hepatic allografts. Results reveal that KC induced apoptosis and lysis of allo-reactive T cells, and this lysis effect was inhibited by anti-FasL antibody.

Details

Language :
English
ISSN :
14765926
Volume :
3
Database :
Academic Search Index
Journal :
Comparative Hepatology
Publication Type :
Academic Journal
Accession number :
28742358
Full Text :
https://doi.org/10.1186/1476-5926-2-S1-S32