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Role of AIM in Corynebacterium-induced granuloma formation in mice.

Authors :
Kuwata, Kazuhisa
Watanabe, Hisami
Yamamoto, Takashi
Miyazaki, Toru
Naito, Makoto
Source :
Comparative Hepatology. 2004 Supplement 1, Vol. 3, p1-3. 3p. 1 Diagram, 2 Graphs.
Publication Year :
2004

Abstract

A conference paper on the role of apoptosis inhibitor expressed by macrophages (AIM) in Corynebacterium-induced granuloma formation in mice is presented. Results reveal the poor repopulation of natural killer T (NKT) cells in middle and late stages of granuloma formation in AIM-/-mice. Apoptosis of NKT cells and T cells was more prominent in AIM-/- mice. These findings indicate that AIM regulates NKT and T cell apoptosis and recruitment and plays a vital role in granuloma formation.

Details

Language :
English
ISSN :
14765926
Volume :
3
Database :
Academic Search Index
Journal :
Comparative Hepatology
Publication Type :
Academic Journal
Accession number :
28742371