Generalized anomeric effect in action: Synthesis and evaluation of stable reducing indolizidine...

Focuses on the synthesis of a series of aminoketalic castanospermine analogues with a stereoelectronically anchored axial hydroxy group at the pseudoanomeric stereocenter to satisfy the need for glucosidase inhibitors that are highly selective for alpha-glucosidases. Development of the polyhydroxylated bicyclic system.