Back to Search
Start Over
Overexpression of Bcl-XL in beta-cells prevents cell death but impairs mitochondrial signal for...
- Source :
-
American Journal of Physiology . Feb2000 Part 1 of 2, Vol. 278 Issue 2, pE340. 12p. 9 Color Photographs, 1 Black and White Photograph, 1 Diagram, 1 Chart, 20 Graphs. - Publication Year :
- 2000
-
Abstract
- Studies the effects of Bcl-XL in the pancreatic beta cell by producing two cell lines using different forms of the rat insulin promoter. Observation of glucose intolerance; Reduction in glucose-induced insulin secretion and hyperglycemia due to overexpression of Bcl-XL and defect in mitochondrial nutrient metabolism.
- Subjects :
- *PANCREATIC beta cells
*INSULIN
*HYPERGLYCEMIA
*SECRETION
Subjects
Details
- Language :
- English
- ISSN :
- 00029513
- Volume :
- 278
- Issue :
- 2
- Database :
- Academic Search Index
- Journal :
- American Journal of Physiology
- Publication Type :
- Academic Journal
- Accession number :
- 2921740