IL-18 binding protein increases spontaneous and IL-1-induced prostaglandin production via inhibition of IFN-...

Authors :: Reznikov, Leonid L.
Soo-Hyun Kim
Source :: Proceedings of the National Academy of Sciences of the United States of America. 02/29/2000, Vol. 97 Issue 5, p2174. 6p. 10 Graphs.
Publication Year :: 2000
Abstract: Investigates interleukin (IL-18) for its ability to induce prostaglandin E... (PGE...) synthesis in human peripheral blood mononuclear cells (PBMC). Isolation of PBMC and whole blood; Mediation of the suppressive effect of IL-18 on PGE... production with the interferon inducing factor; IL-18 binding protein; Causes of increases in PGE... production.

Subjects :: *INTERLEUKINS
*PROSTAGLANDIN synthesis
*BLOOD cells
*INTERFERONS

Language :: English
ISSN :: 00278424
Volume :: 97
Issue :: 5
Database :: Academic Search Index
Journal :: Proceedings of the National Academy of Sciences of the United States of America
Publication Type :: Academic Journal
Accession number :: 2945989
Full Text :: https://doi.org/10.1073/pnas.040582597

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